Name : Anti-TIAM1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2118843954
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TIAM1 |
| Specificity | This antibody reacts specifically with TIAM1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human TIAM1 |
| Gene ID | 7074 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Activates RAC1, Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them, CDC42, and to a lesser extent RHOA, Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | TIAM1 Polyclonal Antibody |
| Other name | Anti-TIAM1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TIAM1 |
| Short name | Anti-TIAM1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-T-cellular lymphoma invasion and metastasis 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BT, Cell surfaces, TIAM1 and IDBG-1597 and ENSG00000156299 and 102724932, Tiam1 and IDBG-174466 and ENSMUSG00000002489 and 21844, ephrin receptor binding, this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0016477 and cell migration and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0031234 and extrinsic component of cytoplasmic side of plasma membrane and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043087 and regulation of GTPase activity and biological process this GO :0044291 and cell-cell contact zone and cellular component this GO :0046875 and ephrin receptor binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048013 and ephrin receptor signaling pathway and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005057: receptor signaling protein activity, this GO :0005057: receptor signaling protein activity and also this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0030676: Rac guanyl-nucleotide exchange factor activity and also this GO :0046875: ephrin receptor binding, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005515: protein binding, this GO :0005543: phospholipid binding, this GO :0030676: Rac guanyl-nucleotide exchange factor activity, this GO :0046875: ephrin receptor binding, 7074, 74139 and IDBG-630064 and ENSBTAG00000017839 and, T-cell lymphoma invasion and metastasis 1 |
| Identity | 11805 |
| Gene | TIAM1 |
| Long gene name | T-cell lymphoma invasion and metastasis 1 |
| Locus | 21q22, 11 |
| Discovery year | 1994-04-22 |
| Entrez gene record | 7074 |
| Pubmed identfication | 8595894 15340013 |
| RefSeq identity | NM_003253 |
| Classification | Rho guanine nucleotide exchange factors Pleckstrin homology domain containing PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000084869 |