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Anti-TIF1 gamma (Polyclonal), ALEXA Fluor 594

Anti-TIF1 gamma (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideT1 gamma
SpecificityThis antibody reacts specifically with TIF1 gamma
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human TIF1 gamma
Gene ID51592
Swiss ProtQ9UPN9
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information According to PubMed:16751102, Inhibits the transcriptional response to TGF-beta/BMP signaling cascade, Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity), May act as a transcriptional repressor, Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade), Plays a role in the control of cell proliferation, Promotes SMAD4 ubiquitination, does not promote a decrease in the level of endogenous SMAD4, nuclear exclusion and degradation via the ubiquitin proteasome pathway, Acts as an E3 ubiquitin-protein ligase
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms hTIF1 Tif1a RNF82 TIF1A
Also known asTIF1 gamma Polyclonal Antibody
Other nameAnti-TIF1 gamma Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTIF1 gamma
Short nameAnti-TIF1 gamma (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TIF1 g (polyclonal)
Alternative techniquepolyclonals
Identity 11812
Gene TRIM24
Long gene name tripartite motif containing 24
Synonyms gene TIF1
Synonyms gene name transcriptional intermediary factor 1 tripartite motif-containing 24
Locus 7q33-q34
Discovery year 1998-12-18
GenBank acession AF009353
Entrez gene record 8805
Pubmed identfication 9115274 9191165
RefSeq identity NM_015905
Classification Tripartite motif containing PHD finger proteins Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000155820

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