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Anti-TLR7 Antibody

Anti-TLR7 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAnti-TLR7
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the anti-TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-TLR7 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9NYK1
PurityPurified
Description Acts via MYD88 and TRAF6, TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA, TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms, [UniProt], cytokine secretion and the inflammatory response (By similarity), leading to NF-kappa-B activation, Toll like receptor 7 is a key component of innate and adaptive immunity
ImmunogenA portion of amino acids 98-128 from the human protein was used as the immunogen for this anti-TLR7 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-TLR7 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTLR7
Short nameAnti-TLR7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-toll-like receptor 7 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Plasma membranes, TLR7 and IDBG-44230 and ENSG00000196664 and 51284, TLR7 and IDBG-639302 and ENSBTAG00000022161 and 493686, Tlr7 and IDBG-185532 and ENSMUSG00000044583 and 170743, siRNA binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008144 and drug binding and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032009 and early pha this GO some and cellular component this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034154 and toll-like receptor 7 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035197 and siRNA binding and molecular function this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0043235 and receptor complex and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003725: double-stranded RNA binding, this GO :0003725: double-stranded RNA binding and also this GO :0003727: single-stranded RNA binding and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding and also this GO :0035197: siRNA binding, this GO :0003727: single-stranded RNA binding, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, this GO :0008144: drug binding, this GO :0035197: siRNA binding, toll-like receptor 7
Identity 15631
Gene TLR7
Long gene name toll like receptor 7
Synonyms gene name toll-like receptor 7
Locus Xp22, 2
Discovery year 2001-04-27
GenBank acession AF240467
Entrez gene record 51284
Pubmed identfication 11022119
RefSeq identity NM_016562
Classification Toll like receptors
Havana BLAST/BLAT OTTHUMG00000021137
Locus Specific Databases Mental Retardation database

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