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Anti-TLX2 (Polyclonal), ALEXA Fluor 594

Anti-TLX2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTLX2
SpecificityThis antibody reacts specifically with TLX2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TLX2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations in the gene encoding mouse Tlx2 lead to congenital anomalies closely resembling neuronal intestinal dysplasia in humans, TLX2, TLX2 is thought to play a role in this disease, The expression pattern of Tlx2, The mouse homolog, Thus, Tlx2, also known as homeobox protein Hox-11L1 (HOX11L1), and shares several critical domains, cranial and entric-nerve gangla, has been detected in dorsal-root ganglia, including an enhancer element in the promotor that is crucial for tissue-specific expression, intestine and heart of adult mice, is a 284 amino acid member of the TLX homeobox family, is highly homologous to mouse Tlx2, neural crest homeobox protein (NCX) or ENX, parasympathetic ganglia and adrenal glands in mouse embryos and in the adrenal glands, suggests that it may play a role in the proliferation or differentiation of the enteric peripheral nervous system, which is a rare condition characterized by hyperplasia of submucosal plexus with giant submucosal ganglia and increased acetylcholinesterase activity in nerve fiber around submucosal blood vessels, which is localized to the nucleus, which is restricted to tissues derived from nerual crest cells, T-cell leukemia homeobox protein 2 (TLX2)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Enx Tlx2 NCX
Also known asTLX2 Polyclonal Antibody
Other nameAnti-TLX2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTLX2
Short nameAnti-TLX2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-T-cell leukemia homeobox 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0008150 and biological process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0048484 and enteric nervous system development and biological process this GO :0050774 and negative regulation of dendrite morphogenesis and biological process, HOX11L1 and NCX, TLX2 and IDBG-57593 and ENSG00000115297 and 3196, TLX2 and IDBG-631278 and ENSBTAG00000016607 and 539041, Tlx2 and IDBG-159907 and ENSMUSG00000068327 and 21909, nuclei, sequence-specific DNA binding, this GO :0001707 and mesoderm formation and biological process this GO :0003674 and molecular function and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, T-cell leukemia homeobox 2
Identity 5057
Gene TLX2
Long gene name T-cell leukemia homeobox 2
Synonyms gene HOX11L1
Synonyms gene name homeo box 11-like 1 T-cell leukemia, homeobox 2
Locus 2p13, 1
Discovery year 1998-08-04
GenBank acession AJ002607
Entrez gene record 3196
Pubmed identfication 10343123
Classification NKL subclass homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000129960

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