Name : Anti-TMEM16A (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3356468152
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TMEM16A |
| Specificity | This antibody reacts specifically with TMEM16A |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human TMEM16A |
| Gene ID | 55107 |
| Swiss Prot | Q5XXA6 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development, Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles, Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | TAOS2 FLJ10261 DOG1 |
| Also known as | TMEM16A Polyclonal Antibody |
| Other name | Anti-TMEM16A Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TMEM16A |
| Short name | Anti-TMEM16A (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-TMEM16A (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 21625 |
| Gene | ANO1 |
| Long gene name | anoctamin 1 |
| Synonyms gene | ORAOV2 TMEM16A |
| Synonyms gene name | calcium activated chloride channel , oral cancer overexpressed 2 transmembrane protein 16A anoctamin 1 |
| Locus | 11q13, 3 |
| Discovery year | 2003-10-16 |
| GenBank acession | BC033036 |
| Entrez gene record | 55107 |
| Pubmed identfication | 15067359 18724360 24692353 |
| RefSeq identity | NM_018043 |
| Classification | Anoctamins |
| Havana BLAST/BLAT | OTTHUMG00000167204 |