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Anti-TMEM2L (Polyclonal), ALEXA Fluor 594

Anti-TMEM2L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTMEM2L
SpecificityThis antibody reacts specifically with TMEM2L
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TMEM2L
Gene ID57214
Swiss ProtQ8WUJ3
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds to hyaluronic acid, Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, In collaboration with HSPA5/BIP, Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium, May be involved in hearing, Positively regulates epithelial-mesenchymal transition (EMT), a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes, and hence tumor cell growth, invasion and cancer dissemination, promotes cancer cell migration in a calcium and PKC-dependent manner, Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IR2155535 TMEM2L HYBID
Also known asTMEM2L Polyclonal Antibody
Other nameAnti-TMEM2L Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTMEM2L
Short nameAnti-TMEM2L (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TMEM2L (polyclonal)
Alternative techniquepolyclonals
Identity 29213
Gene CEMIP
Long gene name cell migration inducing hyaluronan binding protein
Synonyms gene KIAA1199
Synonyms gene name KIAA1199 cell migration inducing protein, hyaluronan binding
Synonyms name hyaluronan-binding protein involved in hyaluronan depolymerization
Locus 15q25, 1
Discovery year 2004-06-29
GenBank acession BC020256
Entrez gene record 57214
Pubmed identfication 14577002 16157444 24573670
RefSeq identity NM_018689
Havana BLAST/BLAT OTTHUMG00000144184

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