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Anti-TMPRSS2 (Polyclonal), ALEXA Fluor 594

Anti-TMPRSS2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTMPRSS2
SpecificityThis antibody reacts specifically with TMPRSS2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Secreted, Extracellular
Antigen SourceKLH conjugated synthetic peptide derived from human TMPRSS2
Gene ID7113
Swiss ProtO15393
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 2, 3, 4a and 4b viruses (HPIV), Essential for spread and pathogenesis of influenza A virus (strains H1N1, Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, H3N2 and H7N9), Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry, human metapneumovirus (HMPV), human parainfluenza 1, involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity, proteolytic cleavage of ACE2, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence, which might promote viral uptake, Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PRSS10
Also known asTMPRSS2 Polyclonal Antibody
Other nameAnti-TMPRSS2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTMPRSS2
Short nameAnti-TMPRSS2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TMPRSS2 (polyclonal)
Alternative techniquepolyclonals
Identity 11876
Gene TMPRSS2
Long gene name serine 2 , transmembrane protease
Locus 21q22, 3
Discovery year 1997-05-09
GenBank acession U75329
Pubmed identfication 9325052
Classification Proteases, serine
Havana BLAST/BLAT OTTHUMG00000086762

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