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Anti-TNIK (Polyclonal), ALEXA Fluor 594

Anti-TNIK (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTNIK
SpecificityThis antibody reacts specifically with TNIK
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TNIK
Gene ID23043
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ESTs have been isolated from human tissue libraries, Northern analysis indicates TNIK expression in human heart, TNIK has been shown to phosphorylate gelsolin, The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells, This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton, and brain, and pancreas, gallbladder and skin, in vitro, including normal amnion, liver, lung, skeletal muscle, the principal intracellular and extracellular actin-severing protein, with lower levels of expression in kidney, TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0551
Also known asTNIK Polyclonal Antibody
Other nameAnti-TNIK Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTNIK
Short nameAnti-TNIK (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TRAF2 and NCK interacting kinase (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005083: small GTPase regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005083: small GTPase regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase
Identity 30765
Gene TNIK
Long gene name TRAF2 and NCK interacting kinase
Locus 3q26, 2-q26, 31
Discovery year 2004-02-26
GenBank acession AF172264
Entrez gene record 23043
Pubmed identfication 9628581 10521462
RefSeq identity XM_039796
Havana BLAST/BLAT OTTHUMG00000159036

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