Name : Anti-TNNI3K (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4540824898
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TNNI3K |
| Specificity | This antibody reacts specifically with TNNI3K |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human TNNI3K |
| Gene ID | 51086 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response, TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, There are four isoforms of TNNI3K that are produced as a result of alternative splicing events, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases, therefore protecting the myocardium from ischemic injury, TNNI3K |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CARK |
| Also known as | TNNI3K Polyclonal Antibody |
| Other name | Anti-TNNI3K Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TNNI3K |
| Short name | Anti-TNNI3K (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-TNNI3K (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 19661 |
| Gene | TNNI3K |
| Long gene name | TNNI3 interacting kinase |
| Locus | 1p31, 1 |
| Discovery year | 2004-01-19 |
| GenBank acession | AF116826 |
| Entrez gene record | 51086 |
| Pubmed identfication | 12721663 |
| RefSeq identity | NM_015978 |
| Havana BLAST/BLAT | OTTHUMG00000171318 |
| Locus Specific Databases | LRG_678 |