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Anti-TORC2 (Ser171) (Polyclonal), ALEXA Fluor 594

Anti-TORC2 (Ser171) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTORC2 Ser171
SpecificityThis antibody reacts specifically with TORC2 (Ser171)
ModificationPhosphorylation
Modification siteSer171
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
Gene ID200186
Swiss ProtQ53ET0
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a coactivator, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR), Enhances the interaction of CREB1 with TAF4, Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells, Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway, Regulates the expression of specific genes such as the steroidogenic gene, StAR, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, in the SIK/TORC signaling pathway, Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TORC2
Also known asTORC2 (Ser171) Polyclonal Antibody
Other nameAnti-TORC2 (Ser171) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTORC2 (Ser171)
Short nameAnti-TORC2 (Ser171) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TORC2 (Ser171) (polyclonal)
Alternative techniquepolyclonals
Identity 27301
Gene CRTC2
Long gene name CREB regulated transcription coactivator 2
Locus 1q21, 3
Discovery year 2005-11-24
GenBank acession AY360172
Entrez gene record 200186
Pubmed identfication 14506290 14536081
RefSeq identity NM_181715
Havana BLAST/BLAT OTTHUMG00000037156

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