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Anti-Torsin A (Polyclonal), ALEXA Fluor 594

Anti-Torsin A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTorsin A
SpecificityThis antibody reacts specifically with Torsin A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Torsin A
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Early-onset torsion dystonia is a movement disorder, Symptoms are believed to result from altered neuronal communication in the basal ganglia, The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family, The gene which encodes TorsinA maps to human chromosome 9q34, The proteins display cytoplasmic distribution, TorsinA comprises 332 amino acids, TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions, TorsinA often performs chaperone-like functions that assist in the assembly, although in some types of neurons localization is perinuclear, characterized by twisting muscle contractures, has been identified as the cause of one form of autosomal dominantly inherited dystonia, operation, or dis-assembly of protein complexes, that begins in childhood, which codes for TorsinA, A mutation of the DYT1 gene
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ14771 TORP1
Also known asTorsin A Polyclonal Antibody
Other nameAnti-Torsin A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTorsin A
Short nameAnti-Torsin A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Torsin A (polyclonal)
Alternative techniquepolyclonals
Identity 11996
Gene TOR2A
Long gene name torsin family 2 member A
Synonyms gene name member A , torsin family 2
Locus 9q34, 11
Discovery year 2000-02-17
GenBank acession AA873275
Entrez gene record 27433
Pubmed identfication 10644435
RefSeq identity NM_130459
Havana BLAST/BLAT OTTHUMG00000020706

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