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Anti-Torsin B (Polyclonal), ALEXA Fluor 594

Anti-Torsin B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTorsin B
SpecificityThis antibody reacts specifically with Torsin B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Torsin B
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding TorsinB are associated with torsion dystonia, Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB contains two PKC (protein kinase C) phosphorylations sites, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development, Via its ability to regulate protein folding, a related family member, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DQ1 MGC4386
Also known asTorsin B Polyclonal Antibody
Other nameAnti-Torsin B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTorsin B
Short nameAnti-Torsin B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Torsin B (polyclonal)
Alternative techniquepolyclonals
Identity 11995
Gene TOR1B
Long gene name torsin family 1 member B
Synonyms gene name member B (torsin B) , torsin family 1
Synonyms name torsin B
Locus 9q34, 11
Discovery year 2000-02-17
GenBank acession AF007872
Entrez gene record 27348
Pubmed identfication 9288096 10644435
RefSeq identity NM_014506
Havana BLAST/BLAT OTTHUMG00000020795

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