Anti-TRP12 (Polyclonal), ALEXA Fluor 594

Anti-TRP12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	TRP12
Specificity	This antibody reacts specifically with TRP12
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Cytoplasm
Antigen Source	KLH conjugated synthetic peptide derived from human TRPV4
Gene ID	59341
Swiss Prot	Q9HBA0
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C
Also known as	TRP12 Polyclonal Antibody
Other name	Anti-TRP12 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	TRP12
Short name	Anti-TRP12 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-TRP12 (polyclonal)
Alternative technique	polyclonals
Identity	18083
Gene	TRPV4
Long gene name	transient receptor potential cation channel subfamily V member 4
Synonyms gene name	member 4 , subfamily V, transient receptor potential cation channel
Synonyms name	osmosensitive transient receptor potential channel 4
Locus	12q24, 11
Discovery year	2002-01-29
GenBank acession	AF263523
Entrez gene record	59341
Pubmed identfication	11025659 11081638 16382100 20037587
RefSeq identity	NM_021625
Classification	Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT	OTTHUMG00000169277
Locus Specific Databases	LRG_372

Anti-TRP12 (Polyclonal), ALEXA Fluor 594

Anti-TRP12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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