Filters

Anti-TRPM4 (Polyclonal), ALEXA Fluor 594

Anti-TRPM4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTRPM4
SpecificityThis antibody reacts specifically with TRPM4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human TRPM4
Gene ID54795
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization, Controls insulin secretion in pancreatic beta-cells, Cs(+) >, Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway, Involved in myogenic constriction of cerebral arteries, It is a cardiac bundle branch disorder characterized by progressive alteration of cardiac conduction through the His-Purkinje system, It leads to complete atrio-ventricular block causing syncope and sudden death, It thereby plays a central role in cadiomyocytes, K(+) >, Li(+)), May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload, Mediates transport of monovalent cations (Na(+) >, Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, While it is activated by increase in intracellular Ca(2+), cochlea hair cells etc, dorsal root and vomeronasal neurons, endocrine pancreas cells, it is impermeable to it, kidney epithelial cells, leading to depolarize the membrane, neurons from entorhinal cortex, which is required for NFAT-dependent IL2 production, with a pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together, Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization, Involvement in disease:Defects in TRPM4 are the cause of progressive familial heart block type 1B (PFHB1B) [MIM:604559]
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ20041
Also known asTRPM4 Polyclonal Antibody
Other nameAnti-TRPM4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTRPM4
Short nameAnti-TRPM4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, member 4 (polyclonal), subfamily M, antibody to-transient receptor potential cation channel
Alternative techniquepolyclonals
Alternative to gene target ATP binding, Plasma membranes, TRPM4 and IDBG-62419 and ENSG00000130529 and 54795, TRPM4 and IDBG-640445 and ENSBTAG00000006139 and 100295930, Trpm4 and IDBG-182463 and ENSMUSG00000038260 and 68667, member 4, subfamily M, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002724 and regulation of T cell cytokine production and biological process this GO :0005216 and ion channel activity and molecular function this GO :0005227 and calcium activated cation channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016925 and protein sumoylation and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005216: ion channel activity, this GO :0005216: ion channel activity and also this GO :0005227: calcium activated cation channel activity and also this GO :0005262: calcium channel activity and also this GO :0005516: calmodulin binding and also this GO :0005524: ATP binding, this GO :0005227: calcium activated cation channel activity, this GO :0005262: calcium channel activity, this GO :0005516: calmodulin binding, this GO :0005524: ATP binding, transient receptor potential cation channel
Identity 17993
Gene TRPM4
Long gene name transient receptor potential cation channel subfamily M member 4
Synonyms gene name member 4 , subfamily M, transient receptor potential cation channel
Locus 19q13, 3
Discovery year 2002-01-11
GenBank acession AK000048
Entrez gene record 54795
Pubmed identfication 11535825 16382100
RefSeq identity NM_017636
Classification Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000183184

Similar products

Subscribe to our Newsletter