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Anti-TRPM5 (Polyclonal), ALEXA Fluor 594

Anti-TRPM5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTRPM5
SpecificityThis antibody reacts specifically with TRPM5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human TRPM5
Gene ID29850
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activated by arachidonic acid in vitro, Activated directly by increases in intracellular Ca(2+), Also activated by a fast intracellular Ca(2+) increase in response to inositol 1, External acidification has 2 effects, Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+), Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials, Is a highly temperature-sensitive, K(+) and Cs(+) ions equally well, May also be involved in sensing semiochemicals, May be involved in perception of bitter, Monovalent-specific, The channel is blocked by extracellular acidification, a fast reversible block of the current and a slower irreversible enhancement of current inactivation, but is impermeable to it, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction, non-selective cation channel that mediates the transport of Na(+), sweet and umami tastes, 4, 5-triphosphate-producing receptor agonists, Voltage-modulated Ca(2+)-activated
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LTRPC5 MTR1
Also known asTRPM5 Polyclonal Antibody
Other nameAnti-TRPM5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTRPM5
Short nameAnti-TRPM5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TRPM5 (polyclonal)
Alternative techniquepolyclonals
Identity 14323
Gene TRPM5
Long gene name transient receptor potential cation channel subfamily M member 5
Synonyms gene name member 5 , subfamily M, transient receptor potential cation channel
Locus 11p15, 5
Discovery year 2002-01-11
GenBank acession AF177473
Entrez gene record 29850
Pubmed identfication 10607831 16382100
RefSeq identity NM_014555
Classification Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000009896

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