Name : Anti-TRPM5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2876287299
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | TRPM5 |
| Specificity | This antibody reacts specifically with TRPM5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human TRPM5 |
| Gene ID | 29850 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Activated by arachidonic acid in vitro, Activated directly by increases in intracellular Ca(2+), Also activated by a fast intracellular Ca(2+) increase in response to inositol 1, External acidification has 2 effects, Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+), Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials, Is a highly temperature-sensitive, K(+) and Cs(+) ions equally well, May also be involved in sensing semiochemicals, May be involved in perception of bitter, Monovalent-specific, The channel is blocked by extracellular acidification, a fast reversible block of the current and a slower irreversible enhancement of current inactivation, but is impermeable to it, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction, non-selective cation channel that mediates the transport of Na(+), sweet and umami tastes, 4, 5-triphosphate-producing receptor agonists, Voltage-modulated Ca(2+)-activated |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | LTRPC5 MTR1 |
| Also known as | TRPM5 Polyclonal Antibody |
| Other name | Anti-TRPM5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | TRPM5 |
| Short name | Anti-TRPM5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-TRPM5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14323 |
| Gene | TRPM5 |
| Long gene name | transient receptor potential cation channel subfamily M member 5 |
| Synonyms gene name | member 5 , subfamily M, transient receptor potential cation channel |
| Locus | 11p15, 5 |
| Discovery year | 2002-01-11 |
| GenBank acession | AF177473 |
| Entrez gene record | 29850 |
| Pubmed identfication | 10607831 16382100 |
| RefSeq identity | NM_014555 |
| Classification | Transient receptor potential cation channels |
| Havana BLAST/BLAT | OTTHUMG00000009896 |