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Anti-TRPV3 (Polyclonal), ALEXA Fluor 594

Anti-TRPV3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTRPV3
SpecificityThis antibody reacts specifically with TRPV3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human TRPV3
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Human TRPV3 is expressed in skin, In addition, It is abundantly expressed in kidney, TRPV3 associates with VR-1 and may modulate VR-1 activity, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1, TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine, The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, an N-linked glycosylation site and three ankyrin repeat regions, and at lower levels in testis, brain, capsaicin-insensitive TRPV3 is expressed at warm temperatures, colon and rectum, dorsal root ganglion, expression increases in response to noxious temperatures, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, jejunum and pancreas, multiple potential phosphorylation sites, placenta, prostate, spinal cord and brain, the 5â, the thermal-sensitive, tongue, trigeminal ganglion, &euro, &trade, -flanking region of TRPV5 contains four putative vitamin D3-responsive elements, Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms VRL3
Also known asTRPV3 Polyclonal Antibody
Other nameAnti-TRPV3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTRPV3
Short nameAnti-TRPV3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TRPV3 (polyclonal)
Alternative techniquepolyclonals
Identity 18084
Gene TRPV3
Long gene name transient receptor potential cation channel subfamily V member 3
Synonyms gene name member 3 , subfamily V, transient receptor potential cation channel
Locus 17p13, 2
Discovery year 2002-07-05
GenBank acession AF514998
Entrez gene record 162514
Pubmed identfication 12016205 12077606 16382100
RefSeq identity NM_145068
Classification Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000090695

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