Anti-TSEN2 (Polyclonal), ALEXA Fluor 594

Anti-TSEN2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	TSEN2
Specificity	This antibody reacts specifically with TSEN2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human TSEN2
Gene ID	80746
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, In addition to its role in pre-tRNA splicing, Isoform 1 seems to carry the active site for 5â, TSEN2 (tRNA-splicing endonuclease subunit Sen2), There are three isoforms of TSEN2 that are produced as a result of alternative splicing events, also known as tRNA-intron endonuclease Sen2, and 3â, extrapyramidal dyskinesia and chorea without spinal cord findings, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex, is thought to link pre-tRNA and pre-mRNA splicing events, splice sites, the heterotetrameric endonuclease complex participates in mRNA processing and, thereby releasing introns and free tRNA molecules with 2', via its association with pre-mRNA processing factors, which is characterized by progressive microencephaly with epilepsy, &euro, &euro, &euro, &trade, &trade, &trade, -splice site cleavage, 3' cyclic phosphates and 5'-OH termini, The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5â
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	SEN2 SEN2L MGC2776
Also known as	TSEN2 Polyclonal Antibody
Other name	Anti-TSEN2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	TSEN2
Short name	Anti-TSEN2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-TSEN2 (polyclonal)
Alternative technique	polyclonals
Identity	28422
Gene	TSEN2
Long gene name	tRNA splicing endonuclease subunit 2
Synonyms gene name	S, cerevisiae) TSEN2 tRNA splicing endonuclease subunit , cerevisiae) tRNA splicing endonuclease 2 homolog (S, tRNA splicing endonuclease 2 homolog (SEN2
Locus	3p25, 2
Discovery year	2005-03-07
GenBank acession	BC019582
Entrez gene record	80746
Pubmed identfication	15109492
RefSeq identity	NM_025265
Classification	tRNA-splicing endonuclease subunits
Havana BLAST/BLAT	OTTHUMG00000129765

Anti-TSEN2 (Polyclonal), ALEXA Fluor 594

Anti-TSEN2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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