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Anti-TTBK2/SCA11 (Polyclonal), ALEXA Fluor 594

Anti-TTBK2/SCA11 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTTBK2/SCA11
SpecificityThis antibody reacts specifically with TTBK2/SCA11
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TTBK2/SCA11
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11), Existing as three alternatively spliced isoforms, It is a relatively benign, Patients show progressive incoordination of gait and often poor coordination of hands, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA), The SCA11 gene, The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation, and maps to human chromosome 15q15, chicken and zebrafish, comprising of 16 exons, cow, dog, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, late-onset, mouse, produces a 5, rat, slowly progressive neurologic disorder, speech and eye movements, the SCA11 gene is conserved in chimpanzee, 2, 244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family, 6-kb transcript in which the longest open reading frame is 3, 732 nucleotides, SCA11 is a 1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0847
Also known asTTBK2/SCA11 Polyclonal Antibody
Other nameAnti-TTBK2/SCA11 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTTBK2/SCA11
Short nameAnti-TTBK2/SCA11 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TTBK2/SCA11 (polyclonal)
Alternative techniquepolyclonals
Identity 19141
Gene TTBK2
Long gene name tau tubulin kinase 2
Synonyms gene SCA11
Synonyms gene name spinocerebellar ataxia 11
Locus 15q15, 2
Discovery year 2003-05-28
GenBank acession AB020654
Entrez gene record 146057
Pubmed identfication 10048485
RefSeq identity NM_173500
Havana BLAST/BLAT OTTHUMG00000175802

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