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Anti-Tuberin (Ser1387) (Polyclonal), ALEXA Fluor 594

Anti-Tuberin (Ser1387) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTuberin Ser1387
SpecificityThis antibody reacts specifically with Tuberin (Ser1387)
ModificationPhosphorylation
Modification siteSer1387
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1387
Gene ID7249
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information At least three isoforms of Tuberin exist, Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking, It may function in vesicular transport, It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, Mutations in tuberin lead to constitutive activation of RAP1A in tumors, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, is implicated as a tumor suppressor, or TSC2 (Tuberous sclerosis complex), suggesting a possible mechanism for its role in regulating cellular growth, Tuberin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LAM, OTTHUMP00000158940, OTTHUMP00000198394, OTTHUMP00000198395, P-TSC2 Ser1387, TSC2, TSC2_HUMAN, TSC4, Tuberin, Tuberin phospho Ser1387, Tuberous sclerosis 2, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog, p-Tuberin Ser1387, FLJ43106, TSC2 Ser1387, Tuberinphospho S1387
Also known asTuberin (Ser1387) Polyclonal Antibody
Other nameAnti-Tuberin (Ser1387) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTuberin (Ser1387)
Short nameAnti-Tuberin (Ser1387) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Tuberin (Ser1387) (polyclonal)
Alternative techniquepolyclonals

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