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Anti-TUSC2 (Polyclonal), ALEXA Fluor 594

Anti-TUSC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideTUSC2
SpecificityThis antibody reacts specifically with TUSC2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human TUSC2
Gene ID11334
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information AKT, Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions, PDGFR, Restoration of TUSC2 function in 3p21, TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, and c-Kit, c-Abl, 3 region where allele losses and genetic alterations occur early and frequently for many human cancers, 3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics, TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FUS1 PAP C3orf11
Also known asTUSC2 Polyclonal Antibody
Other nameAnti-TUSC2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetTUSC2
Short nameAnti-TUSC2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-TUSC2 (polyclonal)
Alternative techniquepolyclonals
Identity 17034
Gene TUSC2
Long gene name tumor suppressor candidate 2
Synonyms gene PDAP2
Synonyms gene name PDGFA associated protein 2
Locus 3p21, 31
Discovery year 2003-09-25
GenBank acession AF055479
Entrez gene record 11334
Pubmed identfication 8780057 11593436
RefSeq identity NM_007275
Havana BLAST/BLAT OTTHUMG00000156877

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