| Vial description | JAK-3, L-JAK, Janus kinase 3 |
| Category | primary antibody |
| Clonality | monoclonal |
| Raised in | Mouse |
| Clone | 5H2 |
| Form | Ascites |
| Reactivity | Mouse, Human |
| Purity | purified |
| Molecular weight | in kDa |
| Source | mammalian |
| Activity | to be determined |
| Range | broad |
| Protein number | P52333 |
| Application | Immunocytochemistry/Immunofluorescence, Western Blot, ELISA |
| Storage | Avoid freeze/thaw cycles, Upon delivery aliquot and store at -20°, C, C for one year, Shipped at 4° |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by acr they should be stored frozen at - 24° |
| Gene target | Tyrosine-protein kinase JAK3 |
| Short name | anti-Tyrosine-protein kinase JAK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-Tyrosine-protein phosphorylation catalyst Janus kinase 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, JAK-3 and JAK3_HUMAN and JAKL and L-JAK and LJAK, JAK3 and IDBG-37201 and ENSG00000105639 and 3718, Jak3 and IDBG-166648 and ENSMUSG00000031805 and 16453, Plasma membranes, this GO :0002731 and negative regulation of dendritic cell cytokine production and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007260 and tyrosine phosphorylation of STAT protein and biological process this GO :0007262 and STAT protein import into nucleus and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019903: protein phosphatase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019903: protein phosphatase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0045221 and negative regulation of FasL biosynthetic process and biological process this GO :0045626 and negative regulation of T-helper 1 cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070232 and regulation of T cell apoptotic process and biological process this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0070669 and response to interleukin-2 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0070672 and response to interleukin-15 and biological process this GO :0071104 and response to interleukin-9 and biological process this GO :2000670 and positive regulation of dendritic cell apoptotic process and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 44422 and IDBG-641863 and ENSBTAG00000020904 and 538276, Janus kinase 3 |
| Identity | 6193 |
| Gene | JAK3 |
| Long gene name | Janus kinase 3 |
| Synonyms | L-JAK JAKL LJAK JAK3_HUMAN JAK-3 |
| Synonyms name | tyrosine-protein kinase JAK3 leukocyte Janus kinase |
| Locus | 19p13, 11 |
| Discovery year | 1994-12-19 |
| GenBank acession | U31601 |
| Entrez gene record | 3718 |
| Pubmed identfication | 8921370 9226382 |
| RefSeq identity | NM_000215 |
| Havana BLAST/BLAT | OTTHUMG00000165648 |
| Locus Specific Databases | JAK3base: Mutation registry for autosomal recessive severe combined JAK3 deficiency LRG_77 |