Name : Anti-UACA (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5906128127
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | UACA |
| Specificity | This antibody reacts specifically with UACA |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human UACA |
| Gene ID | 55075 |
| Swiss Prot | Q9BZF9 |
| Applications | IF(ICC), IF(IHC-P) |
| Applications with corresponding dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species | Bovine, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity), Interaction with ARF6 may modulate cell shape and motility after injury (By similarity), LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation, Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility, Promotes apoptosis by regulating three pathways, Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress, apoptosome up-regulation, Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ10128 KIAA1561 |
| Also known as | UACA Polyclonal Antibody |
| Other name | Anti-UACA Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | UACA |
| Short name | Anti-UACA (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-uveal autoantigen with coiled-coil domains and ankyrin repeats (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BT, UACA and IDBG-19585 and ENSG00000137831 and 55075, Uaca and IDBG-173915 and ENSMUSG00000034485 and 72565, nuclei, protein binding, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0008150 and biological process and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0009411 and response to UV and biological process this GO :0016020 and membrane and cellular component this GO :0042307 and positive regulation of protein import into nucleus and biological process this GO :0042347 and negative regulation of NF-kappaB import into nucleus and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005515: protein binding, this GO :0005515: protein binding, 26227 and IDBG-645550 and ENSBTAG00000013982 and 281559, uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Identity | 15947 |
| Gene | UACA |
| Long gene name | uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Synonyms name | nucling |
| Locus | 15q23 |
| Discovery year | 2001-06-29 |
| GenBank acession | AF322916 |
| Entrez gene record | 55075 |
| Pubmed identfication | 11162650 10997877 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133363 |