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Anti-Ube2B (Polyclonal), ALEXA Fluor 594

Anti-Ube2B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideUbe2B
SpecificityThis antibody reacts specifically with Ube2B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Ube2B
Gene ID7320
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164', H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), In vitro catalyzes 'Lys-11'-, May be involved in neurite outgrowth, Required for postreplication repair of UV-damaged DNA, and is also a prerequisite for H3K4me and H3K79me formation, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination, elongation by RNA polymerase II, it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1, telomeric silencing, Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms UBC2 HHR6B RAD6B
Also known asUbe2B Polyclonal Antibody
Other nameAnti-Ube2B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetUbe2B
Short nameAnti-Ube2B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ubiquitin-conjugating enzyme E2B (polyclonal)
Alternative techniquepolyclonals
Identity 12473
Gene UBE2B
Long gene name ubiquitin conjugating enzyme E2 B
Synonyms gene name ubiquitin-conjugating enzyme E2B (RAD6 homolog) ubiquitin-conjugating enzyme E2B
Locus 5q31, 1
Discovery year 1992-12-02
GenBank acession M74525
Entrez gene record 7320
Pubmed identfication 1559696
RefSeq identity NM_003337
Classification Ubiquitin conjugating enzymes E2
Havana BLAST/BLAT OTTHUMG00000129120

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