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Anti-Ubiquitin D (Polyclonal), ALEXA Fluor 594

Anti-Ubiquitin D (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideUbiquitin D
SpecificityThis antibody reacts specifically with Ubiquitin D
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Ubiquitin D
Gene ID10537
Swiss ProtO15205
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Conjugation ability activated by UBA6, May be involved in dendritic cell (DC) maturation, May be involved in the formation of aggresomes when proteasome is saturated or impaired, Mediates apoptosis in a caspase-dependent manner, Mediates mitotic non-disjunction and chromosome instability, Probably functions as a survival factor, Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2), Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha, Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs), by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN), in a NUB1L-dependent manner, in long-term in vitro culture and cancers, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses, Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FAT10
Also known asUbiquitin D Polyclonal Antibody
Other nameAnti-Ubiquitin D Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetUbiquitin D
Short nameAnti-Ubiquitin D (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Ubiquitin D (polyclonal)
Alternative techniquepolyclonals
Identity 18795
Gene UBD
Long gene name ubiquitin D
Locus 6p22, 1
Discovery year 2002-06-19
GenBank acession Y12653
Entrez gene record 10537
Pubmed identfication 9368598 8662070
Havana BLAST/BLAT OTTHUMG00000031289

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