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Anti-VAPB (Polyclonal), ALEXA Fluor 594

Anti-VAPB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideVAPB
SpecificityThis antibody reacts specifically with VAPB
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human VAPB
Gene ID9217
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in VAPB are a cause of proximal adult autosomal dominant spinal muscular atrophy [MIM:182980], Spinal muscular atrophies are neurodegenerative disorders characterized by degeneration of lower motor neurons, The patients show a benign course, This form is a late adult onset form of the disease (after age 20 years), also called late onset spinal muscular atrophy Finkel type, leading to progressive paralysis muscular atrophy, most of them remaining ambulatory 10 to 40 years after clinical onset, VAPB contains 1 MSP domain and it may play a role in vesicle trafficking
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms VAP-B VAP-C ALS8
Also known asVAPB Polyclonal Antibody
Other nameAnti-VAPB Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetVAPB
Short nameAnti-VAPB (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-VAPB (polyclonal)
Alternative techniquepolyclonals
Identity 12649
Gene VAPB
Long gene name VAMP associated protein B and C
Synonyms gene name VAMP (vesicle-associated membrane protein)-associated protein B and C
Locus 20q13, 32
Discovery year 1999-03-19
GenBank acession AF086628
Entrez gene record 9217
Pubmed identfication 9920726
Havana BLAST/BLAT OTTHUMG00000032840
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_656

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