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Anti-VE Cadherin (Polyclonal), ALEXA Fluor 594

Anti-VE Cadherin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideVE Cadherin
SpecificityThis antibody reacts specifically with VE Cadherin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from mouse Vascular endolial cell cadherin
Gene ID12562
Swiss ProtP55284
Applications IF(ICC), IF(IHC-P)
Applications with corresponding dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Mouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen, PARD3, Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, TIAM1 and RAP1B to the cell junction, These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B, They preferentially interact with themselves in a homophilic manner in connecting cells, This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions, cadherins may thus contribute to the sorting of heterogeneous cell types, Cadherins are calcium-dependent cell adhesion proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AA48225, Cadherin-5, Cd144, Cdh5, VE-Cad, VE-cadherin, VECD, VEcad, Vascular endothelial cadherin, Vec, 7B4
Also known asVE Cadherin Polyclonal Antibody
Other nameAnti-VE Cadherin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetVE Cadherin
Short nameAnti-VE Cadherin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-VE Cadherin (polyclonal)
Alternative techniquepolyclonals

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