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Anti-VEGFR3 (Polyclonal), ALEXA Fluor 594

Anti-VEGFR3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideVEGFR3
SpecificityThis antibody reacts specifically with VEGFR3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from mouse VEGFR3
Gene ID14257
Swiss ProtP35917
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information MAPK3/ERK1 signaling pathway, Mediates activation of the MAPK1/ERK2, Mediates phosphorylation of PIK3R1, Modulates KDR signaling by forming heterodimers, Phosphorylates SHC1, Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', Promotes proliferation, Signaling by activated FLT4 leads to enhanced production of VEGFC, and of AKT1 at 'Ser-473', and of the AKT1 signaling pathway, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development, and regulates angiogenic sprouting, and to a lesser degree VEGFA, of MAPK8 and the JUN signaling pathway, survival and migration of endothelial cells, the regulatory subunit of phosphatidylinositol 3-kinase, thereby creating a positive feedback loop that enhances FLT4 signaling, Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms VEGFR3 PCL
Also known asVEGFR3 Polyclonal Antibody
Other nameAnti-VEGFR3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetVEGFR3
Short nameAnti-VEGFR3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-VEGFR3 (polyclonal)
Alternative techniquepolyclonals
Identity 3767
Gene FLT4
Long gene name fms related tyrosine kinase 4
Synonyms gene name fms-related tyrosine kinase 4
Locus 5q35, 3
Discovery year 1991-10-25
GenBank acession X68203
Entrez gene record 2324
Pubmed identfication 1319394
Classification I-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000130931

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