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Anti-Villin (Polyclonal), ALEXA Fluor 594

Anti-Villin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideVillin
SpecificityThis antibody reacts specifically with Villin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Villin
Gene ID7429
Swiss ProtP09327
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Appears to regulate cell death by maintaining mitochondrial integrity, Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities, Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity, Binds phosphatidylinositol 4, Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, Plays a role in the actin nucleation, Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium, Regulates the intestinal epithelial cell morphology, Upon S, actin filament bundle assembly, actin filament capping and severing, binds LPA with higher affinity than PIP2, cell invasion, cell migration and apoptosis, chemotaxis and wound repair, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination, 5-bisphosphate (PIP2) and lysophosphatidic acid (LPA), Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments, flexneri cell infection
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asVillin Polyclonal Antibody
Other nameAnti-Villin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetVillin
Short nameAnti-Villin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Villin (polyclonal)
Alternative techniquepolyclonals
Identity 30906
Gene VILL
Long gene name villin like
Locus 3p22, 2
Discovery year 2004-07-28
Entrez gene record 50853
Pubmed identfication 9179494
RefSeq identity NM_015873
Classification Gelsolin/villins
Havana BLAST/BLAT OTTHUMG00000130814

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