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Anti-Vinexin (Polyclonal), ALEXA Fluor 594

Anti-Vinexin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideVinexin
SpecificityThis antibody reacts specifically with Vinexin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Vinexin
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Although Vinexin alpha and Vinexin beta have different roles within the cell, Like Vinexin alpha, Localized to cell junctions in both the cytoplasm and the cytoskeleton, Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, Vinexin alpha functions to promote Actin stress fiber formation, Vinexin beta is localized to cell junctions in the cytoplasm, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, brain, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation, designated Vinexin alpha and Vinexin beta, heart, including placenta, liver, pancreas and skeletal muscle, playing an important role in modification of the Actin cytoskeleton, signal transduction and cytoskeletal organization throughout the cell, Vinexin is a 671 amino acid protein that is expressed as two isoforms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SCAM-1 SH3D4 vinexin
Also known asVinexin Polyclonal Antibody
Other nameAnti-Vinexin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetVinexin
Short nameAnti-Vinexin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Vinexin (polyclonal)
Alternative techniquepolyclonals
Identity 30907
Gene SORBS3
Long gene name sorbin and SH3 domain containing 3
Locus 8p21, 3
Discovery year 2005-09-28
Entrez gene record 10174
Pubmed identfication 9885244 12510380
RefSeq identity NM_005775
Havana BLAST/BLAT OTTHUMG00000131728

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