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Anti-Vitamin D Receptor/VDR, ALEXA Fluor 594
Anti-Vitamin D Receptor/VDR, ALEXA Fluor 594 size: 100 microliters 489
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BIOSS POLYCLONAL ANTIBODIES
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489
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Vitamin D Receptor/VDR |
| Specificity | This antibody reacts specifically with Vitamin D Receptor/VDR |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human Vitamin D Receptor |
| Gene ID | 7421 |
| Swiss Prot | P11473 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Plays a central role in calcium homeostasis, Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, Regulates transcription of hormone sensitive genes via its association with the WINAC complex, Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes, a chromatin-remodeling complex, an essential step for VDR-promoter association, which mediates the interaction with acetylated histones, Nuclear hormone receptor |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NR1I1 PPP1R163 |
| Also known as | Vitamin D Receptor/VDR Antibody |
| Other name | Anti-Vitamin D Receptor/VDR |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Vitamin D Receptor/VDR |
| Short name | Fluor 594, Anti-Vitamin D Receptor/VDR |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, 25- dihydroxyvitamin D3) receptor, antibody to-Vitamin D Receptor/vitamin D (1 |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007165 and signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007595 and lactation and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008434 and vitamin D3 receptor activity and molecular function this GO :0009887 and organ morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010839 and negative regulation of keratinocyte proliferation and biological process this GO :0010980 and positive regulation of vitamin D 24-hydroxylase activity and biological process this GO :0038183 and bile acid signaling pathway and biological process this GO :0038186 and lithocholic acid receptor activity and molecular function this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045618 and positive regulation of keratinocyte differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046697 and decidualization and biological process this GO :0046965 and retinoid X receptor binding and molecular function this GO :0050892 and intestinal absorption and biological process this GO :0060058 and positive regulation of apoptotic process involved in mammary gland involution and biological process this GO :0060558 and regulation of calcidiol 1-monooxygenase activity and biological process this GO :0060745 and mammary gland branching involved in pregnancy and biological process this GO :0070561 and vitamin D receptor signaling pathway and biological process this GO :0070644 and vitamin D response element binding and molecular function this GO :1902098 and calcitriol binding and molecular function this GO :1902121 and lithocholic acid binding and molecular function, NR1I1 and PPP1R163, VDR and IDBG-29237 and ENSG00000111424 and 7421, VDR and IDBG-633008 and ENSBTAG00000016414 and 533656, Vdr and IDBG-179227 and ENSMUSG00000022479 and 22337, lithocholic acid binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001501 and skeletal system development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003707: steroid hormone receptor activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0008434: vitamin D3 receptor activity and also this GO :0038186: lithocholic acid receptor activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0046965: retinoid X receptor binding and also this GO :0070644: vitamin D response element binding and also this GO :1902098: calcitriol binding and also this GO :1902121: lithocholic acid binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003707: steroid hormone receptor activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0008434: vitamin D3 receptor activity, this GO :0038186: lithocholic acid receptor activity, this GO :0043565: sequence-specific DNA binding, this GO :0046965: retinoid X receptor binding, this GO :0070644: vitamin D response element binding, this GO :1902098: calcitriol binding, this GO :1902121: lithocholic acid binding, 25- dihydroxyvitamin D3) receptor, vitamin D (1 |
| Identity | 12679 |
| Gene | VDR |
| Long gene name | vitamin D (1, 25- dihydroxyvitamin D3) receptor |
| Synonyms name | protein phosphatase 1, regulatory subunit 163 |
| Locus | 12q13, 11 |
| Discovery year | 1989-06-30 |
| GenBank acession | J03258 |
| Entrez gene record | 7421 |
| Pubmed identfication | 1662663 |
| Classification | Nuclear hormone receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000169890 |
| Locus Specific Databases | ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |