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Anti-WBP2 (Polyclonal), ALEXA Fluor 594

Anti-WBP2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideWBP2
SpecificityThis antibody reacts specifically with WBP2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human WBP2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, The domain mediates protein-protein interactions through the binding of polyproline ligands, The gene encoding WBP2 is located on human chromosome 17, WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2), colon, early onset breast cancer and a predisposition to cancers of the ovary, including structural, prostate gland and fallopian tubes, regulatory and signaling proteins, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms WBP-2 GRAMD6
Also known asWBP2 Polyclonal Antibody
Other nameAnti-WBP2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetWBP2
Short nameAnti-WBP2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-WBP2 (polyclonal)
Alternative techniquepolyclonals
Identity 12738
Gene WBP2
Long gene name WW domain binding protein 2
Locus 17q25, 1
Discovery year 1999-11-26
GenBank acession U79458
Entrez gene record 23558
Pubmed identfication 7644498 26881968 23233354
RefSeq identity NM_012478
Classification GRAM domain containing
Havana BLAST/BLAT OTTHUMG00000179896

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