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Anti-XRCC4 (Polyclonal), ALEXA Fluor 594

Anti-XRCC4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideXRCC4
SpecificityThis antibody reacts specifically with XRCC4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human XRCC4
Gene ID7518
Swiss ProtQ13426
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends, Binds to DNA and to DNA ligase IV (LIG4), The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4, Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asXRCC4 Polyclonal Antibody
Other nameAnti-XRCC4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetXRCC4
Short nameAnti-XRCC4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-X-ray repair complementing defective repair in Chinese hamster cells 4 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target XRCC4 and IDBG-32219 and ENSG00000152422 and 7518, XRCC4 and IDBG-646520 and ENSBTAG00000024275 and 613590, Xrcc4 and IDBG-171005 and ENSMUSG00000021615 and 108138, nuclei, protein C-terminus binding, this GO :0001701 and in utero embryonic development and biological process this GO :0002328 and pro-B cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005958 and DNA-dependent protein kinase-DNA ligase 4 complex and cellular component this GO :0006266 and DNA ligation and biological process this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0010165 and response to X-ray and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016032 and viral process and biological process this GO :0030054 and cell junction and cellular component this GO :0032807 and DNA ligase IV complex and cellular component this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033151 and V(D)J recombination and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051103 and DNA ligation involved in DNA repair and biological process this GO :0051351 and positive regulation of ligase activity and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071285 and cellular response to lithium ion and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, X-ray repair complementing defective repair in Chinese hamster cells 4
Identity 12831
Gene XRCC4
Long gene name X-ray repair cross complementing 4
Synonyms gene name X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms name X-ray repair, complementing defective, repair in Chinese hamster DNA repair protein XRCC4
Locus 5q14, 2
Discovery year 1990-10-16
GenBank acession AB017445
Entrez gene record 7518
Pubmed identfication 1697445 7665175
RefSeq identity NM_022550
Havana BLAST/BLAT OTTHUMG00000131319

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