Anti-YB1(Ser102) (Polyclonal), ALEXA Fluor 594

Anti-YB1(Ser102) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	YB1 Ser102
Specificity	This antibody will recognize Y Box-binding protein 3 when phosphorylated at Ser134YB1(Ser102)
Modification	Phosphorylation
Modification site	Ser102
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus, Cytoplasm
Antigen Source	KLH conjugated synthetic phosphopeptide derived from human YB1 around the phosphorylation site of Ser102
Gene ID	4904
Swiss Prot	P67809
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	YB-1 YB1 DBPB NSEP-1 MDR-NF1 BP-8 CSDB CSDA2
Also known as	YB1(Ser102) Polyclonal Antibody
Other name	Anti-YB1(Ser102) Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	YB1(Ser102)
Short name	Anti-YB1(Ser102) (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-YB1(Ser102) (polyclonal)
Alternative technique	polyclonals
Identity	8014
Gene	YBX1
Long gene name	Y-box binding protein 1
Synonyms gene	NSEP1
Synonyms gene name	nuclease sensitive element binding protein 1
Locus	1p34, 2
Discovery year	1993-10-20
GenBank acession	BC013838
Entrez gene record	4904
Pubmed identfication	1891370 3174636
RefSeq identity	NM_004559
Classification	Y box binding proteins
Havana BLAST/BLAT	OTTHUMG00000007523

Anti-YB1(Ser102) (Polyclonal), ALEXA Fluor 594

Anti-YB1(Ser102) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

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