Anti-ZFYVE27 (Polyclonal), ALEXA Fluor 594

Anti-ZFYVE27 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	ZFYVE27
Specificity	This antibody reacts specifically with ZFYVE27
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human ZFYVE27
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Five isoforms of ZFYVE27 exist as a result of alternative splicing events, Mutations in the gene encoding ZFTVE27 affect neuronal intracellular trafficking in the corticospinal tract and are thought to lead to hereditary spastic paraplegia (HSP), The FYVE domain is a cysteine-rich domain of about 70 amino acids that plays a role in the endosomal localization of the FYVE-finger proteins, ZFYVE27, a multi-pass membrane protein, a neurodegenerative disorder, a protein that is primarily involved in microtubule dynamics and severing, also known as SPG33, and a majority of these proteins serve as regulators of endocytic membrane trafficking, characterized by progressive paralysis of the legs, is a 411 amino acid member of the FYVE-finger family of proteins, is an endosomal protein that binds to Spastin, vesicular trafficking and endosomal trafficking, which is caused by impaired axonal transport, Zinc finger FYVE domain-containing protein 27 (ZFYVE27)
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	FLJ32919 SPG33
Also known as	ZFYVE27 Polyclonal Antibody
Other name	Anti-ZFYVE27 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	ZFYVE27
Short name	Anti-ZFYVE27 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-ZFYVE27 (polyclonal)
Alternative technique	polyclonals
Identity	26559
Gene	ZFYVE27
Long gene name	zinc finger FYVE-type containing 27
Synonyms gene name	FYVE domain containing 27 , zinc finger
Synonyms name	protrudin
Locus	10q24, 2
Discovery year	2004-03-05
GenBank acession	BC030621
Entrez gene record	118813
Pubmed identfication	14702039
RefSeq identity	NM_144588
Classification	Zinc fingers FYVE-type
Havana BLAST/BLAT	OTTHUMG00000018867

Anti-ZFYVE27 (Polyclonal), ALEXA Fluor 594

Anti-ZFYVE27 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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