Name : Anti-ZNF312B/FEZF1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8956991444
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ZNF312B/FEZF1 |
| Specificity | This antibody reacts specifically with ZNF312B/FEZF1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ZNF312B |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | FEZF1 (Fez family zinc finger protein 1), In FEZF1-deficient mice, Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumor mass in mice, There are three isoforms of FEZF1 that are produced as a result of alternative splicing events, When FEZF1 translocates to the nucleus, also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, axons of olfactory neurons do not reach the olfactory bulb, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice, it induces KRAS overexpression, resulting in activation of ERK-signaling, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules, which is covered by the CNS basal lamina, Olfactory sensory neurons contain olfactory receptors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | ZNF312B/FEZF1 Polyclonal Antibody |
| Other name | Anti-ZNF312B/FEZF1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ZNF312B/FEZF1 |
| Short name | Anti-ZNF312B/FEZF1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ZNF312B/FEZF1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 22788 |
| Gene | FEZF1 |
| Long gene name | FEZ family zinc finger 1 |
| Synonyms gene | ZNF312B |
| Synonyms gene name | zinc finger protein 312B |
| Locus | 7q31, 32 |
| Discovery year | 2006-08-14 |
| GenBank acession | AY726588 |
| Entrez gene record | 389549 |
| RefSeq identity | NM_001024613 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000157091 |