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Anti-ZNRF2 (Polyclonal), ALEXA Fluor 594

Anti-ZNRF2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideZNRF2
SpecificityThis antibody reacts specifically with ZNRF2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ZNRF2
Gene ID223082
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Expressed at high levels in brain tissue, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Upon DNA damage, ZNRF2 (zinc and ring finger 2), ZNRF2 is subject to phosphorylation, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity, also known as RNF202, as well as the endosome and the cell junction, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, probably by ATR or ATM, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RNF202
Also known asZNRF2 Polyclonal Antibody
Other nameAnti-ZNRF2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetZNRF2
Short nameAnti-ZNRF2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ZNRF2 (polyclonal)
Alternative techniquepolyclonals
Identity 22316
Gene ZNRF2
Long gene name zinc and ring finger 2
Synonyms gene name E3 ubiquitin protein ligase , zinc and ring finger 2
Locus 7p14, 3
Discovery year 2004-07-29
GenBank acession AF513707
Entrez gene record 223082
Pubmed identfication 22797923
RefSeq identity NM_147128
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000097759

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