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Anti-Zonula occludens protein 3, ALEXA Fluor 594

Anti-Zonula occludens protein 3, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideZonula occludens protein 3
SpecificityThis antibody reacts specifically with Zonula occludens protein 3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Zonula occludens protein 3
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In addition, Many of the tight junction-associated proteins are members of the membrane-associated guanylate kinase (MAGUK) family and include occludin, These proteins are thought to have both structural and signaling roles, ZO-1, ZO-1 expression is significantly reduced in many breast cancer lines (8), ZO-1 forms complexes with either ZO-2 or ZO-3 (4), ZO-2 and ZO-3 (1, ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, ZO-2 is not expressed in nonepithelial tissue (2, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, and unlike ZO-1, at tight junction stands, occludin and F-actin, the SH3 domain and the guanylate kinase (GuK) domain (3), these proteins can also associate with claudin, where they provide a linkage between the actin cytoskeleton and the tight junction (5-7), which is also expressed at cell junctions of cardiac myocytes, 2), 3), Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TJP3, Tight junction protein ZO-3, Tight junction protein ZO3, ZO3, ZO3_HUMAN, Zona occludens protein 3, Zonula occludens protein 3, Tight junction protein 3, ZO-3
Also known asZonula occludens protein 3 Antibody
Other nameAnti-Zonula occludens protein 3
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetZonula occludens protein 3
Short name Fluor 594, Anti-Zonula occludens protein 3
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Zonula occludens protein 3

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