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Anti-ZWILCH (Polyclonal), ALEXA Fluor 594

Anti-ZWILCH (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideZWILCH
SpecificityThis antibody reacts specifically with ZWILCH
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ZWILCH
Gene ID55055
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Mutations were discovered in Zwilch, The Drosophila Zwilch forms a complex with both ROD Rough Deal) and ZWINT (Zeste-White 10, The human Zwilch, The role of Zwilch in complex is thought to be evolutionarily conserved because the human homologs of Zwilch, These mutations may contribute in part to the chromosomal instability phenotype of colorectal tumor cells, This complex is important for chromosome segregation because it recruits cytoplasmic Dynein to the kinetochore and plays a crucial role in the spindle checkpoint, ZWINT and ROD coimmunoprecipitate in a human cell line called HeLa, ZWINT and ROD complex localizes to the kinetochores at prometaphase, ZWINT and ROD during a screen for mutations in alleles encoding putative chromosome instability genes in cases of human colorectal cancer, also designated ZW10) proteins, Zwilch is the human homolog of the Drosophila Zwilch protein
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ10036 KNTC1AP
Also known asZWILCH Polyclonal Antibody
Other nameAnti-ZWILCH Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetZWILCH
Short nameAnti-ZWILCH (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, homolog (Drosophila) (polyclonal), kinetochore associated, antibody to-Zwilch
Alternative techniquepolyclonals
Alternative to gene target Cytoplasm, ZWILCH and IDBG-18211 and ENSG00000174442 and 55055, ZWILCH and IDBG-645460 and ENSBTAG00000005213 and 534811, Zwilch and IDBG-175909 and ENSMUSG00000032400 and 68014, homolog (Drosophila), kinetochore associated, protein binding, this GO :0000278 and mitotic cell cycle and biological process this GO :0000776 and kinetochore and cellular component this GO :0000777 and condensed chromosome kinetochore and cellular component this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, Zwilch
Identity 25468
Gene ZWILCH
Long gene name zwilch kinetochore protein
Synonyms gene name Zwilch, homolog (Drosophila) , kinetochore associated
Locus 15q22, 31
Discovery year 2005-07-25
GenBank acession AK023175
Entrez gene record 55055
Pubmed identfication 12686595
RefSeq identity NM_017975
Havana BLAST/BLAT OTTHUMG00000133194

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