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AOA1/Aprataxin Antibody

AOA1/Aprataxin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAOA1/Aprataxin Primary Polyclonal Antibody
Also known asAOA1/Aprataxin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAOA1/Aprataxin
SpecificityThis is a highly specific antibody against AOA1/Aprataxin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AOA1/Aprataxin
Gene ID number54840
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AOA, AOA, AOA1, AOA1, APTX, APTX, APTX_HUMAN, AXA 1, AXA1, AXA1, Aprataxin, Aprataxin, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, EAOH, EAOH, EOAHA, EOAHA, FHA HIT, FHA HIT, FHA-HIT, FLJ20157, FLJ20157, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein, Forkhead-associated domain histidine triad-like protein, MGC1072, MGC1072, AOA 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAOA1/Aprataxin
Short nameAOA1/Aprataxin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAOA1/Aprataxin (Antibody to)
Alternative techniqueantibodies
Identity 15984
Gene APTX
Long gene name aprataxin
Synonyms gene AXA1
Synonyms gene name ataxia 1, early onset with hypoalbuminemia
Synonyms FLJ20157 AOA AOA1 EAOH EOAHA
Locus 9p21, 1
Discovery year 2001-07-16
GenBank acession AK000164
Entrez gene record 54840
Pubmed identfication 11586299 11586300
RefSeq identity NM_017692
Havana BLAST/BLAT OTTHUMG00000019759

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