Name : AOA1/Aprataxin Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2814951820
| Long name | ALEXA FLUOR 594 Conjugated, AOA1/Aprataxin Polyclonal Antibody |
| Also known as | Anti-AOA1/Aprataxin PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | AOA1/Aprataxin |
| Specificity | This is a highly specific antibody against AOA1/Aprataxin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AOA1/Aprataxin |
| Gene ID Number | 54840 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ20157 AOA AOA1 EAOH EOAHA |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | AOA1/Aprataxin |
| Short name | AOA1/Aprataxin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, AOA1/Aprataxin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15984 |
| Gene | APTX |
| Long gene name | aprataxin |
| Synonyms gene | AXA1 |
| Synonyms gene name | ataxia 1, early onset with hypoalbuminemia |
| Locus | 9p21, 1 |
| Discovery year | 2001-07-16 |
| GenBank acession | AK000164 |
| Entrez gene record | 54840 |
| Pubmed identfication | 11586299 11586300 |
| RefSeq identity | NM_017692 |
| Havana BLAST/BLAT | OTTHUMG00000019759 |