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AOA1/Aprataxin Antibody, FITC Conjugated

AOA1/Aprataxin Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, AOA1/Aprataxin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAOA1/Aprataxin
SpecificityThis is a highly specific antibody against AOA1/Aprataxin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human AOA1/Aprataxin
Gene ID number54840
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ20157 AOA AOA1 EAOH EOAHA
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAOA1/Aprataxin Conjugated
Short name FITC Conjugated, AOA1/Aprataxin Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, AOA1/Aprataxin (Antibody to)
Alternative techniqueantibodies
Identity 15984
Gene APTX
Long gene name aprataxin
Synonyms gene AXA1
Synonyms gene name ataxia 1, early onset with hypoalbuminemia
Locus 9p21, 1
Discovery year 2001-07-16
GenBank acession AK000164
Entrez gene record 54840
Pubmed identfication 11586299 11586300
RefSeq identity NM_017692
Havana BLAST/BLAT OTTHUMG00000019759

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