Name : AP2 alpha Antibody (TFAP2A, Activator protein 2)
Supplier : NJS POLY
Price :199
SKU : GEN8369380360
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Activator protein 2), AP2 alpha (TFAP2A |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the AP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This AP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P05549 |
| Purity | Antigen affinity |
| Description | AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle, AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, C/EBP alpha and MYC, They also suppress a number of genes including MCAM/MUC18, body wall, face, limbs and neural tube development, Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes |
| Immunogen | A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AP2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Activator protein 2), AP2 alpha (TFAP2A |
| Short name | Activator protein 2), AP2 alpha Antibody (TFAP2A |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Activator protein 2), AP2 a (Antibody to) (TFAP2A |
| Alternative technique | antibodies |
| Identity | 11742 |
| Gene | TFAP2A |
| Long gene name | transcription factor AP-2 alpha |
| Synonyms gene | TFAP2 AP2TF |
| Synonyms gene name | transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha) transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| Synonyms | AP-2 |
| Locus | 6p24, 3 |
| Discovery year | 1991-09-12 |
| GenBank acession | X52611 |
| Entrez gene record | 7020 |
| Pubmed identfication | 1916817 3063603 |
| RefSeq identity | NM_003220 |
| Havana BLAST/BLAT | OTTHUMG00000014235 |