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APAF1 Antibody, ALEXA FLUOR 488

APAF1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, APAF1 Polyclonal Antibody
Also known asAnti-APAF1CT PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPAF1CT
SpecificityThis is a highly specific antibody against APAF1CT
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1200-1248/1248
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apaf-1
Gene ID Number317
Swiss ProtO14727
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Isoform 6 is less effective in inducing apoptosis, This activation requires ATP, leading to the activation of caspase-3 and apoptosis, Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms CED4 APAF-1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APAF1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetAPAF1
Short nameAPAF1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, apoptotic peptidase activating factor 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ADP binding, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007399 and nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0030900 and forebrain development and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0043531 and ADP binding and molecular function this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072432 and response to G1 DNA damage checkpoint signaling and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902510 and regulation of apoptotic DNA fragmentation and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0042802: identical protein binding and also this GO :0043531: ADP binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0042802: identical protein binding, this GO :0043531: ADP binding, apoptotic peptidase activating factor 1
Identity 576
Gene APAF1
Long gene name apoptotic peptidase activating factor 1
Synonyms gene name apoptotic protease activating factor apoptotic peptidase activating factor
Locus 12q23, 1
Discovery year 1998-01-20
GenBank acession AF013263
Entrez gene record 317
Pubmed identfication 9267021 10702682
RefSeq identity NM_181861, 1
Classification Caspase recruitment domain containing Apoptosome WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000170214

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