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APC11 Antibody, ALEXA FLUOR 594

APC11 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, APC11 Polyclonal Antibody
Also known asAnti-APC11 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPC11
SpecificityThis is a highly specific antibody against APC11
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC11
Gene ID Number51529
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen APC, APC is phosphorylated, APC is under tight control by a number of regulatory factors, APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2), CDC20 and CDH1 directly bind to APC and activates APCâ, CDH1 and MAD2, In addition, In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, Specifically, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk), including CDC20, or cyclosome, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis, thus preventing APC activation, &euro, &trade, Comprising more than ten subunits, s cyclin-ubiquitination activity
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms HSPC214 APC11 Apc11p MGC882
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetAPC11
Short nameAPC11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, APC11 (Antibody to)
Alternative techniqueantibodies
Identity 14452
Gene ANAPC11
Long gene name anaphase promoting complex subunit 11
Synonyms gene name anaphase promoting complex subunit 11 (yeast APC11 homolog)
Locus 17q25, 3
Discovery year 2001-03-08
GenBank acession AF247565
Entrez gene record 51529
Pubmed identfication 10922056
RefSeq identity NM_016476
Classification Anaphase promoting complex
Havana BLAST/BLAT OTTHUMG00000177982

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