APCL/APC2 Antibody

APCL/APC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	APCL/APC2 Primary Polyclonal Antibody
Also known as	APCL/APC2 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	APCL/APC2
Specificity	This is a highly specific antibody against APCL/APC2
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APCL/APC2
Gene ID number	10297
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	2843 amino acids in length, APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin, APC has been found to be associated with structural components of intracellular junctions, E cadherin, Interactions between cytoskeleton and the APC, The cloning of the APC gene revealed a ubiquitously expressed protein, These polyps invariably progress to colon cancer in addition to other extracolonic manifestations, are characterized by numerous adenomatous polyps throughout the entire colon, b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion, b/g catenin complex are mediated by a-catenin, familial adenomatous polyposis (FAP) and Gardnerâ, which is frequently mutated in patients suffering from FAP and GS, &euro, &trade, The adenomatous polyposis syndromes, s syndrome (GS)
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	APC2_HUMAN, APCL, Adenomatous polyposis coli protein-like, Adenomatous polyposis coli protein 2
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	APCL/APC2
Short name	APCL/APC2 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	APCL/APC2 (Antibody to)
Alternative technique	antibodies
Identity	24036
Gene	APC2
Long gene name	APC2, WNT signaling pathway regulator
Synonyms gene name	adenomatosis polyposis coli 2
Synonyms	APCL
Synonyms name	adenomatous polyposis coli like
Locus	19p13, 3
Discovery year	2004-03-18
Entrez gene record	10297
Pubmed identfication	9823329 10021369
RefSeq identity	NM_005883
Classification	Armadillo repeat containing
Havana BLAST/BLAT	OTTHUMG00000180059

APCL/APC2 Antibody

APCL/APC2 Antibody size: 0.1ml 263

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