Name : APCL/APC2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1513927708
| Long name | ALEXA FLUOR 488 Conjugated, APCL/APC2 Polyclonal Antibody |
| Also known as | Anti-APCL/APC2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | APCL/APC2 |
| Specificity | This is a highly specific antibody against APCL/APC2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APCL/APC2 |
| Gene ID Number | 10297 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | 2843 amino acids in length, APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin, APC has been found to be associated with structural components of intracellular junctions, E cadherin, Interactions between cytoskeleton and the APC, The cloning of the APC gene revealed a ubiquitously expressed protein, These polyps invariably progress to colon cancer in addition to other extracolonic manifestations, are characterized by numerous adenomatous polyps throughout the entire colon, b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion, b/g catenin complex are mediated by a-catenin, familial adenomatous polyposis (FAP) and Gardnerâ, which is frequently mutated in patients suffering from FAP and GS, &euro, &trade, The adenomatous polyposis syndromes, s syndrome (GS) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | APCL |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APCL/APC2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | APCL/APC2 |
| Short name | APCL/APC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, APCL/APC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24036 |
| Gene | APC2 |
| Long gene name | APC2, WNT signaling pathway regulator |
| Synonyms gene name | adenomatosis polyposis coli 2 |
| Synonyms name | adenomatous polyposis coli like |
| Locus | 19p13, 3 |
| Discovery year | 2004-03-18 |
| Entrez gene record | 10297 |
| Pubmed identfication | 9823329 10021369 |
| RefSeq identity | NM_005883 |
| Classification | Armadillo repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000180059 |