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APCL/APC2 Antibody, ALEXA FLUOR 488

APCL/APC2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, APCL/APC2 Polyclonal Antibody
Also known asAnti-APCL/APC2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPCL/APC2
SpecificityThis is a highly specific antibody against APCL/APC2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APCL/APC2
Gene ID Number10297
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen 2843 amino acids in length, APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin, APC has been found to be associated with structural components of intracellular junctions, E cadherin, Interactions between cytoskeleton and the APC, The cloning of the APC gene revealed a ubiquitously expressed protein, These polyps invariably progress to colon cancer in addition to other extracolonic manifestations, are characterized by numerous adenomatous polyps throughout the entire colon, b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion, b/g catenin complex are mediated by a-catenin, familial adenomatous polyposis (FAP) and Gardnerâ, which is frequently mutated in patients suffering from FAP and GS, &euro, &trade, The adenomatous polyposis syndromes, s syndrome (GS)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms APCL
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APCL/APC2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetAPCL/APC2
Short nameAPCL/APC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, APCL/APC2 (Antibody to)
Alternative techniqueantibodies
Identity 24036
Gene APC2
Long gene name APC2, WNT signaling pathway regulator
Synonyms gene name adenomatosis polyposis coli 2
Synonyms name adenomatous polyposis coli like
Locus 19p13, 3
Discovery year 2004-03-18
Entrez gene record 10297
Pubmed identfication 9823329 10021369
RefSeq identity NM_005883
Classification Armadillo repeat containing
Havana BLAST/BLAT OTTHUMG00000180059

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