Filters

APCL/APC2 Antibody, Biotin Conjugated

APCL/APC2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, APCL/APC2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPCL/APC2
SpecificityThis is a highly specific antibody against APCL/APC2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human APCL/APC2
Gene ID number10297
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2843 amino acids in length, APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin, APC has been found to be associated with structural components of intracellular junctions, E cadherin, Interactions between cytoskeleton and the APC, The cloning of the APC gene revealed a ubiquitously expressed protein, These polyps invariably progress to colon cancer in addition to other extracolonic manifestations, are characterized by numerous adenomatous polyps throughout the entire colon, b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion, b/g catenin complex are mediated by a-catenin, familial adenomatous polyposis (FAP) and Gardnerâ, which is frequently mutated in patients suffering from FAP and GS, &euro, &trade, The adenomatous polyposis syndromes, s syndrome (GS)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms APCL
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPCL/APC2 Conjugated
Short name Conjugated, APCL/APC2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, APCL/APC2 (Antibody to)
Alternative techniqueantibodies
Identity 24036
Gene APC2
Long gene name APC2, WNT signaling pathway regulator
Synonyms gene name adenomatosis polyposis coli 2
Synonyms name adenomatous polyposis coli like
Locus 19p13, 3
Discovery year 2004-03-18
Entrez gene record 10297
Pubmed identfication 9823329 10021369
RefSeq identity NM_005883
Classification Armadillo repeat containing
Havana BLAST/BLAT OTTHUMG00000180059

Subscribe to our Newsletter