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APCL/APC2 Antibody, FITC Conjugated

APCL/APC2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, APCL/APC2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPCL/APC2
SpecificityThis is a highly specific antibody against APCL/APC2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human APCL/APC2
Gene ID number10297
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2843 amino acids in length, APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin, APC has been found to be associated with structural components of intracellular junctions, E cadherin, Interactions between cytoskeleton and the APC, The cloning of the APC gene revealed a ubiquitously expressed protein, These polyps invariably progress to colon cancer in addition to other extracolonic manifestations, are characterized by numerous adenomatous polyps throughout the entire colon, b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion, b/g catenin complex are mediated by a-catenin, familial adenomatous polyposis (FAP) and Gardnerâ, which is frequently mutated in patients suffering from FAP and GS, &euro, &trade, The adenomatous polyposis syndromes, s syndrome (GS)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms APCL
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPCL/APC2 Conjugated
Short name FITC Conjugated, APCL/APC2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, APCL/APC2 (Antibody to)
Alternative techniqueantibodies
Identity 24036
Gene APC2
Long gene name APC2, WNT signaling pathway regulator
Synonyms gene name adenomatosis polyposis coli 2
Synonyms name adenomatous polyposis coli like
Locus 19p13, 3
Discovery year 2004-03-18
Entrez gene record 10297
Pubmed identfication 9823329 10021369
RefSeq identity NM_005883
Classification Armadillo repeat containing
Havana BLAST/BLAT OTTHUMG00000180059

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