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APEX2 Antibody, Cy7 Conjugated

APEX2 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, APEX2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPEX2
SpecificityThis is a highly specific antibody against APEX2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range300-350/518
Subcellular location Mitochondrion, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human APEX2
Gene ID number27301
Swiss ProtQ9UBZ4
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 3'-phosphodiesterase activities, Displays also double-stranded DNA 3'-5' exonuclease, In the nucleus functions in the PCNA-dependent BER pathway, Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, Required for proper cell cycle progression during proliferation of peripheral lymphocytes, Required for somatic hypermutation (SHM) and DNA cleavage step of class switch recombination (CSR) of immunoglobulin genes, Shows fairly strong 3'-phosphodiesterase activity involved in the removal of 3'-damaged termini formed in DNA by oxidative agents, Shows robust 3'-5' exonuclease activity on 3'-recessed heteroduplex DNA and is able to remove mismatched nucleotides preferentially, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends, Function as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms APEXL2 APE2 XTH2 ZGRF2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetAPEX2 Conjugated
Short name Conjugated, APEX2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, APEX2 (Antibody to)
Alternative techniqueantibodies
Identity 17889
Gene APEX2
Long gene name apurinic/apyrimidinic endodeoxyribonuclease 2
Synonyms gene name APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Synonyms name GRF-type containing 2 , zinc finger
Locus Xp11, 21
Discovery year 2002-07-22
GenBank acession AB021260
Entrez gene record 27301
Pubmed identfication 11376153
Classification Zinc fingers GRF-type
Havana BLAST/BLAT OTTHUMG00000021642
Locus Specific Databases Mental Retardation database

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