Name : Apg12 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8950327391
| Long name | ALEXA FLUOR 488 Conjugated, Apg12 Polyclonal Antibody |
| Also known as | Anti-Apg12 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Apg12 |
| Specificity | This is a highly specific antibody against Apg12 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 137-187/187 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apg12 |
| Gene ID Number | 9140 |
| Swiss Prot | O94817 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus, The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes, The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS, is essential for its function, Ubiquitin-like protein involved in autophagy vesicles formation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | APG12 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Apg12 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Apg12 |
| Short name | Apg12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Apg12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 588 |
| Gene | ATG12 |
| Long gene name | autophagy related 12 |
| Synonyms gene | APG12L |
| Synonyms gene name | Apg12 (autophagy 12, S, cerevisiae) , cerevisiae) ATG12 autophagy related 12 homolog (S, cerevisiae)-like APG12 autophagy 12-like (S |
| Synonyms name | APG12 autophagy 12-like |
| Locus | 5q22, 3 |
| Discovery year | 1999-10-01 |
| GenBank acession | AB017507 |
| Entrez gene record | 9140 |
| Pubmed identfication | 9852036 |
| RefSeq identity | NM_004707 |
| Classification | Autophagy related |
| Havana BLAST/BLAT | OTTHUMG00000128889 |